Best American mystery series

When a young boy vanishes, a small town uncovers a mystery involving secret experiments, terrifying supernatural forces, and one strange little girl.

Dexter Morgan, a blood spatter pattern analyst for the Miami Metro Police also leads a secret life as a serial killer, hunting down criminals who have slipped through the cracks of justice.

Stripped of everything, the survivors of a horrific plane crash must work together to stay alive. But the island holds many secrets.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

When they were boys, Sam and Dean Winchester lost their mother to a mysterious and demonic supernatural force. Subsequently, their father raised them to be soldiers. He taught them about the paranormal evil that lives in the dark corners and on the back roads of America ... and he taught them how to kill it. Now, the Winchester brothers crisscross the country in their '67 Chevy Impala, battling every kind of supernatural threat they encounter along the way.

CIA officer Carrie Mathison is tops in her field despite being bipolar, which makes her volatile and unpredictable. With the help of her long-time mentor Saul Berenson, Carrie fearlessly risks everything, including her personal well-being and even sanity, at every turn.

FBI Special Agent Olivia Dunham, brilliant but formerly institutionalized scientist Walter Bishop and his scheming, reluctant son Peter uncover a deadly mystery involving a series of unbelievable events and realize they may be a part of a larger, more disturbing pattern that blurs the line between science fiction and technology.

An American anthology police detective series utilizing multiple timelines in which investigations seem to unearth personal and professional secrets of those involved, both within or outside the law.

An anthology horror drama series centering on different characters and locations, including a house with a murderous past, an asylum, a witch coven, a freak show, a hotel, a farmhouse in Roanoke, a cult, the apocalypse and a summer camp.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

Wanda Maximoff and Vision—two super-powered beings living idealized suburban lives—begin to suspect that everything is not as it seems.

Mark leads a team of office workers whose memories have been surgically divided between their work and personal lives. When a mysterious colleague appears outside of work, it begins a journey to discover the truth about their jobs.

John Reese, former CIA paramilitary operative, is presumed dead and teams up with reclusive billionaire Finch to prevent violent crimes in New York City by initiating their own type of justice. With the special training that Reese has had in Covert Operations and Finch's genius software inventing mind, the two are a perfect match for the job that they have to complete. With the help of surveillance equipment, they work "outside the law" and get the right criminal behind bars. 

Everyone knows the name Commissioner Gordon. He is one of the crime world's greatest foes, a man whose reputation is synonymous with law and order. But what is known of Gordon's story and his rise from rookie detective to Police Commissioner? What did it take to navigate the multiple layers of corruption that secretly ruled Gotham City, the spawning ground of the world's most iconic villains? And what circumstances created them – the larger-than-life personas who would become Catwoman, The Penguin, The Riddler, Two-Face and The Joker?

Thanks to a Japanese scientist's invention of synthetic blood, vampires have progressed overnight from legendary monsters to fellow citizens. And while humans have been safely removed from the menu, many remain apprehensive about these creatures "coming out of the coffin." Religious leaders, government officials, and vampire fundamentalists around the world have chosen their sides. But in the small Louisiana town of Bon Temps, the jury is still out.

Wednesday Addams is sent to Nevermore Academy, a bizarre boarding school where she attempts to master her psychic powers, stop a monstrous killing spree of the town citizens, and solve the supernatural mystery that affected her family 25 years ago — all while navigating her new relationships.

A thriller set two hundred years in the future following the case of a missing young woman who brings a hardened detective and a rogue ship's captain together in a race across the solar system to expose the greatest conspiracy in human history.

After a teenage girl's perplexing suicide, a classmate receives a series of tapes that unravel the mystery of her tragic choice.

The exploits of FBI Special Agents Fox Mulder and Dana Scully who investigate X-Files: marginalized, unsolved cases involving paranormal phenomena. Mulder believes in the existence of aliens and the paranormal while Scully, a skeptic, is assigned to make scientific analyses of Mulder's discoveries that debunk Mulder's work and thus return him to mainstream cases.

Flashing between past and present, a fractured family confronts haunting memories of their old home and the terrifying events that drove them from it.

Patrick Jane, a former celebrity psychic medium, uses his razor sharp skills of observation and expertise at "reading" people to solve serious crimes with the California Bureau of Investigation.

A modern-day drama about a crime-solving duo that cracks the NYPD's most impossible cases. Following his fall from grace in London and a stint in rehab, eccentric Sherlock escapes to Manhattan where his wealthy father forces him to live with his worst nightmare - a sober companion, Dr. Watson.

A small town is suddenly and inexplicably sealed off from the rest of the world by an enormous transparent dome. While military forces, the government and the media positioned outside of this surrounding barrier attempt to break it down, a small group of people inside attempt to figure out what the dome is, where it came from, and when (and if) it will go away.

When Steven Grant, a mild-mannered gift-shop employee, becomes plagued with blackouts and memories of another life, he discovers he has dissociative identity disorder and shares a body with mercenary Marc Spector. As Steven/Marc’s enemies converge upon them, they must navigate their complex identities while thrust into a deadly mystery among the powerful gods of Egypt.

A sexy, suspense-driven legal thriller about a group of ambitious law students and their brilliant, mysterious criminal defense professor. They become entangled in a murder plot and will shake the entire university and change the course of their lives.

In exchange for his freedom, charming con artist Neal Caffrey provides his expertise to help straight-man FBI agent Peter Burke catch elusive white-collar criminals.

After Portland homicide detective Nick Burkhardt discovers he's descended from an elite line of criminal profilers known as "Grimms," he increasingly finds his responsibilities as a detective at odds with his new responsibilities as a Grimm.

An elite team of FBI profilers analyze the country's most twisted criminal minds, anticipating their next moves before they strike again. The Behavioral Analysis Unit's most experienced agent is David Rossi, a founding member of the BAU who returns to help the team solve new cases.

Twin brother and sister Dipper and Mabel Pines are in for an unexpected adventure when they spend the summer helping their great uncle Stan run a tourist trap in the mysterious town of Gravity Falls, Oregon.

Follow the intergalactic adventures of Capt. Jean-Luc Picard and his loyal crew aboard the all-new USS Enterprise NCC-1701D, as they explore new worlds.

Follow the exploits of various guests and employees at an exclusive tropical resort over the span of a week as with each passing day, a darker complexity emerges in these picture-perfect travelers, the hotel’s cheerful employees and the idyllic locale itself.

Based on the Pretty Little Liars series of young adult novels by Sara Shepard, the series follows the lives of four girls — Spencer, Hanna, Aria, and Emily — whose clique falls apart after the disappearance of their queen bee, Alison. One year later, they begin receiving messages from someone using the name "A" who threatens to expose their secrets — including long-hidden ones they thought only Alison knew.

Some of literature's most terrifying characters, including Dr. Frankenstein, Dorian Gray, and iconic figures from the novel Dracula are lurking in the darkest corners of Victorian London. Penny Dreadful is a frightening psychological thriller that weaves together these classic horror origin stories into a new adult drama.

The body of Laura Palmer is washed up on a beach near the small Washington state town of Twin Peaks. FBI Special Agent Dale Cooper is called in to investigate her strange demise only to uncover a web of mystery that ultimately leads him deep into the heart of the surrounding woodland and his very own soul.

A "contemporary prequel" to the 1960 film Psycho, depicting the life of Norman Bates and his mother Norma prior to the events portrayed in Hitchcock's film, albeit in a different fictional town and in a modern setting. The series begins after the death of Norma's husband, when she purchases a motel located in a coastal Oregon town so she and Norman can start a new life.

A spin-off from The Vampire Diaries and set in New Orleans, The Originals centers on the Mikaelson siblings, otherwise known as the world's original vampires: Klaus, Elijah, and Rebekah. Now Klaus must take down his protégé, Marcel, who is now in charge of New Orleans, in order to re-take his city, as he originally built New Orleans. Klaus departed from the city after being chased down by his father Mikael, while it was being constructed and Marcel took charge. As Klaus has returned after many years, his ego has provoked him to become the king of the city. "Every King needs an heir" says Klaus, accepting the unborn child. The child is a first to be born to a hybrid and a werewolf.

Set in an alternate history where “superheroes” are treated as outlaws, “Watchmen” embraces the nostalgia of the original groundbreaking graphic novel while attempting to break new ground of its own.

An exclusive group of privileged teens from a posh prep school on Manhattan's Upper East Side whose lives revolve around the blog of the all-knowing albeit ultra-secretive Gossip Girl.

The world's leading deception researcher, Dr. Cal Lightman, studies facial expression, body language and tone of voice to determine when a person is lying and why, which helps law enforcement and government agencies uncover the truth. But his skills also make it easier for him to deceive others.

Prairie Johnson, blind as a child, comes home to the community she grew up in with her sight restored. Some hail her a miracle, others a dangerous mystery, but Prairie won’t talk with the FBI or her parents about the seven years she went missing.

Set in the present, the series offers a bold, subversive take on Archie, Betty, Veronica and their friends, exploring the surreality of small-town life, the darkness and weirdness bubbling beneath Riverdale’s wholesome facade.

Thanks to his police officer father's efforts, Shawn Spencer spent his childhood developing a keen eye for detail (and a lasting dislike of his dad). Years later, Shawn's frequent tips to the police lead to him being falsely accused of a crime he solved. Now, Shawn has no choice but to use his abilities to perpetuate his cover story: psychic crime-solving powers, all the while dragging his best friend, his dad, and the police along for the ride.

Unravel the mystery of a nightmarish town in middle America that traps all those who enter. As the unwilling residents fight to keep a sense of normalcy and search for a way out, they must also survive the threats of the surrounding forest – including the terrifying creatures that come out when the sun goes down.

Three strangers share an obsession with true crime and suddenly find themselves wrapped up in one.

Across continents and decades, five brilliant friends make earth-shattering discoveries as the laws of science unravel and an existential threat emerges.

After a night of partying with a female stranger, a man wakes up to find her stabbed to death and is charged with her murder.

When Emily Thorne moves to the Hamptons, everyone wonders about the new girl, but she knows everything about them, including what they did to her family. Years ago, they took everything from her. Now, one by one, she's going to make them pay.

An ex-con becomes the traveling partner of a conman who turns out to be one of the older gods trying to recruit troops to battle the upstart deities. Based on Neil Gaiman's fantasy novel.

As her 16th birthday nears, Sabrina must choose between the witch world of her family and the human world of her friends. Based on the Archie comic.

A detective in a small Pennsylvania town investigates a local murder while trying to keep her life from falling apart.

Tom Kirkman, a low-level cabinet member is suddenly appointed President of the United States after a catastrophic attack during the State of the Union kills everyone above him in the Presidential line of succession.

The Killing is an American crime drama television series based upon the Danish television series Forbrydelsen. Set in Seattle, Washington, the series follows the various murder investigations by homicide detectives Sarah Linden and Stephen Holder.

Brought together by a midnight phone call, an FBI agent and a cybersecurity expert must unravel an ever-growing web of political conspiracies.

Looking down on her friends and family isn't a way of life for Mary Alice Young... it's a way of death. One day, in her perfect house, in the loveliest of suburbs, Mary Alice ended it all. Now she's taking us into the lives of her family, friends and neighbors, commenting from her elevated P.O.V.

A preacher sets out on a mission to make the almighty himself confess his sin of abandoning the world. With his best friend Cassidy, an alcoholic Irish vampire, his love Tulip, a red blooded gun towing Texan, and the power of genesis, an unholy child born from an angel and a devil, Jesse gives up everything to set the world straight with its creator.

Brakebills University is a secret institution specializing in magic. There, amidst an unorthodox education of spellcasting, a group of twenty-something friends soon discover that a magical fantasy world they read about as children is all too real— and poses grave danger to humanity.

After their dad's murder, three siblings move with their mom to his ancestral estate, where they discover magical keys that unlock powers — and secrets.

The orphaned Baudelaire children face trials, tribulations and the evil Count Olaf, all in their quest to uncover the secret of their parents' death.

In the fictional town of Neptune, California, student Veronica Mars progresses from high school to college while moonlighting as a private investigator under the tutelage of her detective father.

A young man returns to his isolated hometown on Crockett Island, hoping to rebuild his life after serving four years in prison for killing someone in a drunk-driving incident. He arrives at the same time as a mysterious, charismatic young priest who begins to revitalise the town's flagging faith. However, the community's divisions are soon exacerbated by the priest's deeds while mysterious events befall the small town.

After landing from a turbulent but routine flight, the crew and passengers of Montego Air Flight 828 discover five years have passed in what seemed like a few hours. As their new realities become clear, a deeper mystery unfolds and some of the returned passengers soon realize they may be meant for something greater than they ever thought possible.

They're ordinary husband and wife realtors until she undergoes a dramatic change that sends them down a road of death and destruction. In a good way.

Two brothers, Wirt and Greg, find themselves lost in the Unknown; a strange forest adrift in time. With the help of a wise old Woodsman and a foul-tempered bluebird named Beatrice, Wirt and Greg must travel across this strange land, in hope of finding their way home. Join them as they encounter surprises and obstacles on their journey through the wood.

Reporter Camille Preaker confronts the psychological demons from her past when she returns to her hometown to investigate the murders of two young girls.

In the year 2149, the world is dying. The planet is overdeveloped and overcrowded, with the majority of plant and animal life extinct. The future of mankind is in jeopardy, and its only hope for survival is in the distant past. An ordinary family goes on an extraordinary journey back in time to prehistoric Earth as a part of a massive expedition to save the human race.

Ichabod Crane is resurrected and pulled two and a half centuries through time to unravel a mystery that dates all the way back to the founding fathers.